Brock Purdy Is 5-1 Against the Cardinals, and That One Loss Is the Only Hope

Alright 12s, gather 'round, because we gotta talk about something that hits us right in the gut: Brock Purdy. Yeah, *that* Brock Purdy. As we gear up for another brutal NFC West grind, the numbers are in on how this guy handles our division rivals, the Arizona Cardinals, and honestly, it's a gut punch. He's got a shocking 5-1 career record against them. Five wins, just one measly loss. This is the kind of dominance that keeps Mike Macdonald up at night, knowing what we're up against in the division.

Purdy's Near-Perfect Ride Against the Cardinals: The Numbers Don't Lie

This guy has played six career games against the Cardinals, starting five of them, and he's basically owned them, going 5-1. We're talking about a quarterback who completes 70.1% of his passes, tossing for 1,147 yards, lighting up the scoreboard with 12 touchdowns, and only throwing two interceptions. On top of that, he's even rushed for a touchdown, though he has been sacked eight times. His first glimpse of action against Arizona was back in 2022 in Mexico City, where he played seven snaps at the end of a 38-10 San Francisco win. He rushed three times and handed the ball off four times in that one. But it's his starts that really tell the story of consistent pain for the Cardinals: - In the final week of the 2022 season, he absolutely carved them up for a 38-13 victory, going 15-for-20 passing with three touchdowns. - Week 4 of 2023 saw him lead the 49ers to another dominant 35-16 win. He rushed for a touchdown and completed an insane 20-of-21 passes for 283 yards and another score. - Later that 2023 season, i

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n Week 15, the 49ers handed the Cardinals a 45-29 loss. Purdy completed 16-of-25 passes for 242 yards and four touchdowns. That's just nasty work. - Even in 2025, after suffering an injury in the first game of the season, he returned to beat Arizona 41-22 in Week 11, completing 19-of-36 passes for 200 yards and three touchdowns. Seriously, this guy has their number.

That ONE Loss: The Blueprint for Beating Purdy (Maybe?)

Okay, so he's 5-1. That one loss, though, that's what we need to zoom in on. It happened in Week 5 of 2024, a nail-biter where Arizona managed to pull off a 24-23 victory thanks to a last-second field goal by Chad Ryland. This, my friends, was Purdy's worst game against the Cardinals. He went 19-for-35 passing for 244 yards, managed just one touchdown, and threw both of his career interceptions against them in that single game. It wasn't pretty. Later that 2024 season, in Week 18, he didn't even face the Cardinals because the 49ers rested him. Josh Dobbs started in his place, and guess what? Arizona won that one too. So, there's a tiny glimmer of hope, a crack in the armor, but it's small. So, what does this mean for our beloved Seahawks? As the 2026 season rolls around, the 49ers will clash with the Cardinals twice, in Week 3 on the road and then Week 18 at home. Every single snap, every pass, every mistake Purdy makes against Arizona will be under a microscope for us. We need to see if there's any way to replicate that single loss, any weakness we can exploit. The division race is always a brutal fight, and knowing your enemy, especially one who's had *this* much success, is absolutely crucial. We'll be watching, 12s. Always watching. Go Hawks!

This article was created with AI assistance and reviewed by Seattle On Tap editorial staff. Always verify information with official team sources.